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昂特纳贝

维基百科,自由的百科全书
(重定向自HU-308
昂特纳贝
法律規範狀態
法律規範
藥物動力學數據
药物代谢
排泄途徑
识别信息
  • [(1S,2S,5S)-2-[2,6-Dimethoxy-4-(2-methyloctan-2-yl)phenyl]-7,7-dimethyl-4-bicyclo[3.1.1]hept-3-enyl]methanol
CAS号256934-39-1  checkY
PubChem CID
ChemSpider
UNII
KEGG
ChEBI
CompTox Dashboard英语CompTox Chemicals Dashboard (EPA)
化学信息
化学式C27H42O3
摩尔质量414.63 g·mol−1
3D模型(JSmol英语JSmol
  • CCCCCCC(C)(C)C1=CC(=C(C(=C1)OC)[C@H]2C=C([C@@H]3C[C@H]2C3(C)C)CO)OC
  • InChI=1S/C27H42O3/c1-8-9-10-11-12-26(2,3)19-14-23(29-6)25(24(15-19)30-7)20-13-18(17-28)21-16-22(20)27(21,4)5/h13-15,20-22,28H,8-12,16-17H2,1-7H3/t20-,21-,22+/m0/s1
  • Key:CFMRIVODIXTERW-FDFHNCONSA-N

昂特纳贝INNonternabez,开发代号:HU-308PPP-003ARDS-003),分子式C27H42O3,是一种人工合成的HU系列大麻素,由耶路撒冷希伯來大學拉斐尔·梅舒朗团队在1990年代晚期开发[1][2][3]

参考文献

  1. ^ Mechoulam R, Lander N, Breuer A, Zahalka J. Synthesis of the individual, pharmacologically distinct enantiomers of a tetrahydrocannabinol derivative. Tetrahedron Asymmetry. 1990-04-11, 1 (5): 315–318. doi:10.1016/S0957-4166(00)86322-3可免费查阅 (英语). 
  2. ^ Hanus L, Breuer A, Tchilibon S, Shiloah S, Goldenberg D, Horowitz M, et al. HU-308: a specific agonist for CB(2), a peripheral cannabinoid receptor. Proceedings of the National Academy of Sciences of the United States of America. December 1999, 96 (25): 14228–14233. Bibcode:1999PNAS...9614228H. PMC 24419可免费查阅. PMID 10588688. doi:10.1073/pnas.96.25.14228可免费查阅. 
  3. ^ Properties of HU-308 ~ Formula C27H42O3. Pitt Quantum Repository. University of Pittsburgh Department of Chemistry. [2024-06-10]. (原始内容存档于2022-08-17). 

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