E位点 (英语:E site,E for exit )是蛋白质 转译 过程中核糖体 中tRNA 的第三个也是最后一个结合位点 。[ 1] “E”代表出口,并伴有作为第二结合位点的P位点 (peptidyl)和作为第一结合位点的A位点 (aminoacyl)。[ 2]
参考资料
^ Chen, C.; Stevens, B.; Kaur, J.; Smilansky, Z.; Cooperman, B. S.; Goldman, Y. E. Allosteric vs. spontaneous exit-site (E-site) tRNA dissociation early in protein synthesis . Proceedings of the National Academy of Sciences. 2011-10-03, 108 (41): 16980–16985. Bibcode:2011PNAS..10816980C . ISSN 0027-8424 . PMC 3193197 . PMID 21969541 . doi:10.1073/pnas.1106999108 .
^ Kirillov, S., Makarov, E., & Semenkov, Y. (1983). Quantitative study of interaction of deacylated tRNA with Escherichia coli ribosomes. FEBS Letters, 157(1), 91-94. doi :10.1016/0014-5793(83)81122-3
延伸阅读
Sergiev, Petr V.; Lesnyak, Dmitry V.; Kiparisov, Sergey V.; Burakovsky, Dmitry E.; Leonov, Andrei A.; Bogdanov, Alexey A.; Brimacombe, Richard; Dontsova, Olga A. Function of the ribosomal E-site: a mutagenesis study . Nucleic Acids Research. 2005, 33 (18): 6048–6056. ISSN 0305-1048 . PMC 1266066 . PMID 16243787 . doi:10.1093/nar/gki910 .
Molecular Biology of the Gene, 7th Edition, James D. Watson, Tania A. Baker,Stephen P. Bell,Alexander Gann, Michael Levine,Richard Losick, ©2014 Pearson