模板:PBB/5551

穿孔素1
Perforin 1
穿孔素1; Perforin 1
	一個包含Plu-MACPF蛋白的MACPF域結構PDB 2QP2 MACPF域用青色/粉紅色表示；而?棱鏡域則是用橘色表示；兩個鈣原子則是用灰色表示
標識
代號	PRF1; FLH2; HPLH2; P1; PFN1; PFP
擴展標識	遺傳學：170280 鼠基因：97551 同源基因：3698 ChEMBL: 5480 GeneCards: PRF1 Gene
基因本體論描述
分子功能	· calcium ion binding; · protein binding; · wide pore channel activity;
細胞成分	· extracellular region; · plasma membrane; · membrane; · integral component of membrane; · cytoplasmic membrane-bounded vesicle; · endosome lumen; · cytolytic granule;
生物過程	· defense response to tumor cell; · immune response to tumor cell; · apoptotic process; · cellular defense response; · cytolysis; · protein homooligomerization; · defense response to virus; · transmembrane transport;
	Sources: Amigo / QuickGO
RNA表達模式
	更多表達數據
直系同源體
物種	人類
Entrez	5551
Ensembl	ENSG00000180644
UniProt	P14222
mRNA序列	NM_001083116
蛋白序列	NP_001076585
基因位置	Chr 10:; 72.36 – 72.36 Mb
PubMed查詢	[1]
	閱; 論; 編;

參考資料

^ Rosado CJ, Buckle AM, Law RH, Butcher RE, Kan WT, Bird CH, Ung K, Browne KA, Baran K, Bashtannyk-Puhalovich TA, Faux NG, Wong W, Porter CJ, Pike RN, Ellisdon AM, Pearce MC, Bottomley SP, Emsley J, Smith AI, Rossjohn J, Hartland EL, Voskoboinik I, Trapani JA, Bird PI, Dunstone MA, Whisstock JC. A common fold mediates vertebrate defense and bacterial attack. Science. 2007, 317 (5844): 1548–51. PMID 17717151. doi:10.1126/science.1144706.