鈣調磷酸酶

蛋白磷酸酶3，催化亞基，α同工酶
	PDB rendering based on 1aui.
有效結構
PDB	直系同源檢索：PDBe, RCSB
PDB查詢代碼列表
	1AUI, 1M63, 1MF8, 2JOG, 2JZI, 2P6B, 2R28, 2W73
標識
代號	PPP3CA; CALN; CALNA; CALNA1; CCN1; CNA1; PPP2B
擴展標識	遺傳學：114105 鼠基因：107164 同源基因：55497 GeneCards: PPP3CA Gene
EC編號	3.1.3.16
基因本體論描述
分子功能	· protein serine/threonine phosphatase activity; · calcium-dependent protein serine/threonine phosphatase activity; · calcium ion binding; · protein binding; · calmodulin binding; · hydrolase activity; · protein heterodimerization activity;
細胞成分	· soluble fraction; · insoluble fraction; · nucleus; · nucleolus; · cytoplasm; · mitochondrion; · microsome; · cytosol; · cytosol; · calcineurin complex; · membrane; · Z disc;
生物過程	· G1/S transition of mitotic cell cycle; · response to amphetamine; · protein dephosphorylation; · protein import into nucleus; · calcium ion transport; · response to stress; · positive regulation of transcription from RNA polymerase II promoter; · negative regulation of insulin secretion; · skeletal muscle fiber development; · regulation of synaptic transmission; · regulation of excitatory postsynaptic membrane potential; · cellular response to glucose stimulus;
	Sources: Amigo / QuickGO
RNA表達模式
	更多表達數據
直系同源體
	閱; 論; 編;

鈣調磷酸酶^[1]（英語：Calcineurin，CaN）是鈣和鈣調蛋白依賴性的絲氨酸/蘇氨酸蛋白磷酸酶；亦稱為蛋白磷酸酶3（PPP3），舊稱蛋白磷酸酶2B（PP2B）。其在體內的作用為啟動T細胞並可以通過藥物來阻斷這一過程。

鈣調磷酸酶為很多種免疫抑制藥的作用對象如：環孢黴素，吡美莫司和他克莫司。

參考文獻

^ 存档副本. [2021-12-09]. （原始內容存檔於2021-12-09）.

深入閱讀

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外部連結

醫學主題詞表（MeSH）：Calcineurin
eMedicine Dictionary上的Calcineurin

[1] 存档副本. [2021-12-09]. （原始內容存檔於2021-12-09）.

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