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WF-31

维基百科,自由的百科全书
WF-31
识别信息
  • 2-Propanoyl-3-(4-isopropylphenyl)-tropane
PubChem CID
ChemSpider
ChEMBL
化学信息
化学式C20H29NO
摩尔质量299.46 g·mol−1
3D模型(JSmol英语JSmol
  • CCC(=O)C1C2N(C)C(CC2)CC1c3ccc(C(C)C)cc3
  • InChI=1S/C20H29NO/c1-5-19(22)20-17(12-16-10-11-18(20)21(16)4)15-8-6-14(7-9-15)13(2)3/h6-9,13,16-18,20H,5,10-12H2,1-4H3
  • Key:BVSOMKYAWFJCTH-UHFFFAOYSA-N

WF-31(化学名:2-丙酰基-3-(4-异丙基苯基)-莨菪烷,2-Propanoyl-3-(4-isopropylphenyl)-tropane,缩写PIT)是一种含氮有机化合物,分子式C20H29NO,属于可卡因结构类似物,可作为血清素-去甲肾上腺素-多巴胺三重再摄取抑制剂(SNDRI),其对血清素转运体的抑制效果比可卡因强十余倍[1]

参考文献

  1. ^ Porrino LJ, Miller M, Hedgecock AA, Thornley C, Matasi JJ, Davies HM. Local cerebral metabolic effects of the novel cocaine analog, WF-31: comparisons to fluoxetine. Synapse (New York, N.Y.). September 1997, 27 (1): 26–35. PMID 9268062. S2CID 25320475. doi:10.1002/(SICI)1098-2396(199709)27:1<26::AID-SYN3>3.0.CO;2-F. 

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