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奧替庫單抗

維基百科,自由的百科全書
奧替庫單抗
單株抗體
種類完整抗體
目標oxLDL
臨床資料
其他名稱奧替蘇單抗、BI-204、MLDL1278A
ATC碼
  • 未分配
識別資訊
CAS號1314241-10-5
ChemSpider
  • none
UNII

奧替庫單抗INN:Orticumab;開發代號:BI-204MLDL1278A),或譯奧替蘇單抗,是一種人單株抗體,用作抗炎劑並與oxLDL結合。它充當免疫調節劑[1]該藥物可以用來治療動脈粥樣硬化[2]該藥物由BioInvent公司研究開發。[3]

參考資料

  1. ^ World Health Organization. International Nonproprietary Names for Pharmaceutical Substances (INN). Proposed INN: List 107 (PDF). WHO Drug Information. 2012, 26 (2). 
  2. ^ Yao Mattisson, Ingrid; Rattik, Sara; Björkbacka, Harry; Ljungcrantz, Irena; Terrinoni, Manuela; Lebens, Michael; Holmgren, Jan; Fredrikson, Gunilla Nordin; Gullstrand, Birgitta; Bengtsson, Anders A.; Nilsson, Jan. Immune responses against oxidized LDL as possible targets for prevention of atherosclerosis in systemic lupus erythematosus. Vascular Pharmacology. 2021-10-01, 140. ISSN 1537-1891. doi:10.1016/j.vph.2021.106863. 
  3. ^ Recruitment of patients completed in phase II study with BI-204. BioInvent. 2012-03-02 [2024-01-21] (英語).