地特诺
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臨床資料 | |
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商品名 | Betaphrine 倍他福林 |
其他名稱 | Isopropylnorsynephrine, Isopropyloctopamine |
识别信息 | |
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CAS号 | 7376-66-1 ![]() |
PubChem CID | |
ChemSpider | |
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KEGG | |
ChEMBL | |
CompTox Dashboard (EPA) | |
化学信息 | |
化学式 | C11H17NO2 |
摩尔质量 | 195.26 g·mol−1 |
3D模型(JSmol) | |
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地特诺(英語:Deterenol ;亦称 Isopropylnorsynephrine、Isopropyloctopamine;商品名Betaphrine)是一种兴奋剂,可作为β肾上腺素受体激动药。其曾被用作膳食补充剂产品的成分,但由于可能导致心脏骤停而在大多数国家被禁用。[1][2][3][4][5]
参见
参考文献
- ^ Anderson WG. The sympathomimetic activity of N-isopropyloctopamine in vitro. The Journal of Pharmacology and Experimental Therapeutics. June 1983, 225 (3): 553–8. PMID 6306210.
- ^ Mercader J, Wanecq E, Chen J, Carpéné C. Isopropylnorsynephrine is a stronger lipolytic agent in human adipocytes than synephrine and other amines present in Citrus aurantium. Journal of Physiology and Biochemistry. September 2011, 67 (3): 443–52. PMID 21336650. S2CID 22449550. doi:10.1007/s13105-011-0078-2.
- ^ Venhuis B, Keizers P, van Riel A, de Kaste D. A cocktail of synthetic stimulants found in a dietary supplement associated with serious adverse events. Drug Testing and Analysis. June 2014, 6 (6): 578–81. PMID 24802503. doi:10.1002/dta.1664.
- ^ Zhao J, Wang M, Avula B, Khan IA. Detection and quantification of phenethylamines in sports dietary supplements by NMR approach. Journal of Pharmaceutical and Biomedical Analysis. March 2018, 151: 347–355. PMID 29413984. S2CID 46837518. doi:10.1016/j.jpba.2018.01.025
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- ^ Cohen PA, Travis JC, Vanhee C, Ohana D, Venhuis BJ. Nine prohibited stimulants found in sports and weight loss supplements: deterenol, phenpromethamine (Vonedrine), oxilofrine, octodrine, beta-methylphenylethylamine (BMPEA), 1,3-dimethylamylamine (1,3-DMAA), 1,4-dimethylamylamine (1,4-DMAA), 1,3-dimethylbutylamine (1,3-DMBA) and higenamine. Clinical Toxicology. March 2021, 59 (11): 975–981. PMID 33755516. doi:10.1080/15563650.2021.1894333
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