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狗牙花定碱

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狗牙花定碱
Skeletal formula of coronaridine
Ball-and-stick model of the coronaridine molecule
臨床資料
ATC碼
  • 未分配
识别信息
  • Methyl (1S,15R,17S,18S)-17-ethyl-3,13-diazapentacyclo[13.3.1.02,10.04,9.013,18]nonadeca-2(10),4,6,8-tetraene-1-carboxylate
CAS号467-77-6
PubChem CID
ChemSpider
ChEBI
CompTox Dashboard英语CompTox Chemicals Dashboard (EPA)
ECHA InfoCard100.006.727 編輯維基數據鏈接
化学信息
化学式C21H26N2O2
摩尔质量338.45 g·mol−1
3D模型(JSmol英语JSmol
  • CCC1CC2CC3(C1N(C2)CCC4=C3NC5=CC=CC=C45)C(=O)OC
  • InChI=1S/C21H26N2O2/c1-3-14-10-13-11-21(20(24)25-2)18-16(8-9-23(12-13)19(14)21)15-6-4-5-7-17(15)22-18/h4-7,13-14,19,22H,3,8-12H2,1-2H3/t13-,14+,19+,21-/m1/s1
  • Key:NVVDQMVGALBDGE-PZXGUROGSA-N

狗牙花定碱(英語:Coronaridine,也称为18-甲氧羰基伊波加明,18-carbomethoxyibogamine)是一种有机化合物,化学式为C21H26N2O2,是山马茶(学名:Tabernaemontana divaricata)等马蹄花属植物中提取的生物碱[1]

参考文献

  1. ^ Delorenzi JC, Freire-de-Lima L, Gattass CR, de Andrade Costa D, He L, Kuehne ME, Saraiva EM. In vitro activities of iboga alkaloid congeners coronaridine and 18-methoxycoronaridine against Leishmania amazonensis. Antimicrobial Agents and Chemotherapy. July 2002, 46 (7): 2111–2115. PMC 127312可免费查阅. PMID 12069962. doi:10.1128/aac.46.7.2111-2115.2002.