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甘油-3-磷酸脱氢酶 [NAD(P)+]

维基百科,自由的百科全书
甘油-3-磷酸脱氢酶 [NAD(P)+]
识别码
EC編號 1.1.1.94
CAS号 37250-30-9
数据库
IntEnz IntEnz浏览
BRENDA英语BRENDA BRENDA入口
ExPASy英语ExPASy NiceZyme浏览
KEGG KEGG入口
MetaCyc英语MetaCyc 代谢路径
PRIAM英语PRIAM_enzyme-specific_profiles 概述
PDB RCSB PDB PDBj PDBe PDBsum
基因本体 AmiGO / EGO

甘油-3-磷酸脱氢酶 [NAD(P)+](英語:glycerol-3-phosphate dehydrogenase [NAD(P)+]EC 1.1.1.94页面存档备份,存于互联网档案馆)),是一种以NAD+NADP+受体、作用于供体CH-OH基团上的氧化还原酶。这种催化以下酶促反应

sn-甘油-3-磷酸 + NAD(P)+ 磷酸甘油酮 + NAD(P)H + H+

甘油-3-磷酸脱氢酶 [NAD(P)+]主要参与磷酸甘油酯代谢过程。大肠杆菌Escherichia coli)的甘油-3-磷酸脱氢酶 [NAD(P)+]显示出对NADPH的B域的特异性。

参考文献

  • Kito M, Pizer LI. Purification and regulatory properties of the biosynthetic L-glycerol 3-phosphate dehydrogenase from Escherichia coli. J. Biol. Chem. 1969, 244 (12): 3316–3323. PMID 4389388. 
  • Edgar JR, Bell RM. Biosynthesis in Escherichia coli fo sn-glycerol 3-phosphate, a precursor of phospholipid. J. Biol. Chem. 1978, 253 (18): 6348–6353. PMID 355254. 
  • Edgar JR, Bell RM. Biosynthesis in Escherichia coli of sn-glycerol 3-phosphate, a precursor of phospholipid. Kinetic characterization of wild type and feedback-resistant forms of the biosynthetic sn-glycerol-3-phosphate dehydrogenase. J. Biol. Chem. 1978, 253 (18): 6354–6363. PMID 28326. 
  • Edgar JR, Bell RM. Biosynthesis in Escherichia coli of sn-glycerol-3-phosphate, a precursor of phospholipid. Further kinetic characterization of wild type and feedback-resistant forms of the biosynthetic sn-glycerol-3-phosphate dehydrogenase. J. Biol. Chem. 1980, 255 (8): 3492–3497. PMID 6767719.