甲基磺酰氟
甲基磺酰氟 | |||
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IUPAC名 Methanesulfonyl fluoride[1] | |||
别名 | Fumette, Mesyl fluoride | ||
识别 | |||
缩写 | MSF | ||
CAS号 | 558-25-8 ![]() | ||
PubChem | 11207 | ||
ChemSpider | 10734 | ||
SMILES |
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UN编号 | UN3389 | ||
RTECS | PB2975000[2] | ||
MeSH | methanesulfonyl+fluoride | ||
性质 | |||
化学式 | CH3FO2S | ||
摩尔质量 | 98.1 g·mol−1 | ||
外观 | liquid | ||
氣味 | pungent | ||
密度 | 1.427 g/mL[3] | ||
沸点 | 123 - 124 °C(272 K) | ||
溶解性(水) | Reacts | ||
折光度n D |
1.360 [2] | ||
危险性 | |||
GHS危险性符号![]() ![]() | |||
H-术语 | H300, H330, H314, H318 | ||
P-术语 | P301+310, P303+361+353, P304+340, P305+351+338, P320, P330, P405, P501 | ||
主要危害 | Corrosive Highly toxic | ||
相关物质 | |||
其他阴离子 | 甲基磺酰氯 | ||
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。 |
甲基磺酰氟(英語:Methanesulfonyl fluoride,缩写MSF)是一种磺酰卤化合物,是乙酰胆碱酯酶(AChE)的抑制剂,此酶降解乙酰胆碱,一种中樞和周围神经系统中都重要的神经递质[4][5]。
参考文献
- ^ methanesulfonyl fluoride - Compound Summary (CID 11207). PubChem. [July 25, 2012].
- ^ 2.0 2.1 H53460 Methanesulfonyl fluoride, 98%. [July 25, 2012]. (原始内容存档于January 16, 2013).
- ^ METHANESULFONYL FLUORIDE. chembook. [July 25, 2012]. (原始内容存档于2020-01-03).
- ^ Myers, D. K.; Kemp, A. Inhibition of Esterases by the Fluorides of Organic Acids. Nature. 1954, 173 (4392): 33–4. PMID 13119739. doi:10.1038/173033a0.
- ^ Kitz, R; Wilson, IB. Esters of methanesulfonic acid as irreversible inhibitors of acetylcholinesterase. The Journal of Biological Chemistry. 1962, 237: 3245–9. PMID 14033211.