薩伊伊波拉病毒 （Zaire ebolavirus ，EBOV）舊稱EBOV-Z或ZEBOV，是絲狀病毒科 伊波拉病毒屬 的一種病毒 ，為該屬的六種病毒之一[1] 蘇丹伊波拉病毒 （SUDV）、本迪布焦伊波拉病毒 （BDBV）和象牙海岸伊波拉病毒 （TAFV）皆可導致伊波拉出血熱 。歷史上多數伊波拉病毒疫情皆是此病毒株感染所致，例如2013年至2016年的西非伊波拉病毒疫情 [2] [3]
薩伊伊波拉病毒得名自其發現地薩伊共和國 伊波拉河 （今剛果民主共和國 ）[1] 亚布库 （近伊波拉河）爆發疫情 [4] 馬爾堡病毒 的新毒株[5] [6] [7] [8] [9] 原型 Mayinga N'Seka [1] [10] [11]
薩伊伊波拉病毒的感染發生於剛果民主共和國、加彭 與剛果共和國 ，具2或3組重疊基因 （VP35/VP40、GP/VP30與VP24/L，其中後者視VP24使用的轉譯 終止信號而定）[1] rVSV-ZEBOV疫苗 可有效防制薩伊伊波拉病毒感染[12] [13] 蘇丹伊波拉病毒 防治效果不明），於2019年12月獲美國食品藥物管理局 批准[14]
參考文獻
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Zaire ebolavirus Orthoebolavirus zairense
. PMID 21046175. doi:10.1007/s00705-010-0814-x.
