鱼藤素
鱼藤素 | |
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IUPAC名 4′,5′-Dimethoxy-6′′,6′′-dimethyl-6′′H-pyrano[2′′,3′′:7,8]rotenan-4-one | |
系统名 (7aS,13aS)-9,10-Dimethoxy-3,3-dimethyl-13,13a-dihydro-3H-([1]benzopyrano[4,3-e′]benzo[1,2-b:3,4-b′]dipyran)-7(7aH)-one | |
别名 | Deguelin; 3H-Bis(1)benzopyrano (3,4-b:6',5'-e)pyran-7(7aH)-one, 13,13a-dihydro-9,10-dimethoxy-3,3- dimethyl-, (7aS,13aS)-; 3H-Bis(1) benzopyrano(3,4-b:6',5'-e)pyran- 7(7aH)-one, 13,13a-dihydro- 9, 10-dimethoxy-3,3-dimethyl-, (7aS-cis)- |
识别 | |
CAS号 | 522-17-8 ![]() |
PubChem | 107935 |
ChemSpider | 97058 |
SMILES |
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InChI |
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InChIKey | ORDAZKGHSNRHTD-UXHICEINBW |
ChEBI | 4357 |
性质 | |
化学式 | C23H22O6 |
摩尔质量 | 394.42 g/mol g·mol⁻¹ |
熔点 | 171 °C(444 K) |
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。 |
鱼藤素(英語:Deguelin)是一种有机化合物,分子式C23H22O6,属于鱼藤酮类化合物,存在于薄莢豆屬(Lonchocarpus)、鱼藤属(Derris)、灰叶属(Tephrosia)等豆科植物中[1][2]。
参考文献
- ^ Fang N, Casida JE. Cubé resin insecticide: identification and biological activity of 29 rotenoid constituents. J. Agric. Food Chem. May 1999, 47 (5): 2130–6. PMID 10552508. doi:10.1021/jf981188x.
- ^ Udeani GO, Gerhauser C, Thomas CF, et al. Cancer chemopreventive activity mediated by deguelin, a naturally occurring rotenoid. Cancer Res. August 1997, 57 (16): 3424–8. PMID 9270008.
外部链接
- Lee HY, Suh YA, Kosmeder JW, Pezzuto JM, Hong WK, Kurie JM. Deguelin-induced inhibition of cyclooxygenase-2 expression in human bronchial epithelial cells. Clin. Cancer Res. February 2004, 10 (3): 1074–9. PMID 14871987. doi:10.1158/1078-0432.CCR-0833-3
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- Fang N, Casida JE. Anticancer action of cubé insecticide: correlation for rotenoid constituents between inhibition of NADH:ubiquinone oxidoreductase and induced ornithine decarboxylase activities. Proc Natl Acad Sci USA. March 1998, 95 (7): 3380–4. Bibcode:1998PNAS...95.3380F. PMC 19844
. PMID 9520374. doi:10.1073/pnas.95.7.3380
.