Bedoukian反应
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Bedoukian反应(Bedoukian reaction)是指在对甲苯磺酸或乙酸钾存在条件下,醛或酮与乙酸酐共热得到烯醇乙酸酯的反應。它在四氯化碳中溴化得到加成物,经醇解得到缩醛,最后用酸水解缩醛,得到 α-溴代醛或酮。[1][2][3]
碘代缩醛可通过烯醇乙酸酯与氯化碘作用得到。
参见
参考资料
- ^ Paul Z. Bedoukian. Synthesis of Bromoacetals. J. Am. Chem. Soc. 1944, 66 (4): 651–652. doi:10.1021/ja01232a501.
- ^ Paul Z. Bedoukian. A New Synthesis of α-Bromoaldehydes. J. Am. Chem. Soc. 1944, 66 (8): 1325–1327. doi:10.1021/ja01236a037.
- ^ Paul Z. Bedoukian. Preparation of α,β-Unsaturated Aldehyde Dimethyl Acetals and their Free Aldehydes. J. Am. Chem. Soc. 1957, 79 (4): 889–892. doi:10.1021/ja01561a028.