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4-雄烯-3,6,17-三酮

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4-雄烯-3,6,17-三酮
临床资料
给药途径口服
法律规范状态
法律规范
识别信息
  • (10R,13S)-10,13-dimethyl-
    1,7,8,9,10,11,12,13,15,16-
    decahydro-2H-cyclopenta[alpha]phenanthrene-
    3,6,17(14H)-trione
CAS号2243-06-3  checkY
ChemSpider
UNII
CompTox Dashboard英语CompTox Chemicals Dashboard (EPA)
化学信息
化学式C19H24O3
摩尔质量300.39
3D模型(JSmol英语JSmol
熔点220—227 °C(428—441 °F) [2]
  • O=C4\C1=C\C(=O)CC[C@@]1([C@H]3CC[C@@]2(C(=O)CC[C@H]2[C@@H]3C4)C)C
  • InChI=1S/C19H24O3/c1-18-7-5-11(20)9-15(18)16(21)10-12-13-3-4-17(22)19(13,2)8-6-14(12)18/h9,12-14H,3-8,10H2,1-2H3/t12-,13-,14-,18+,19-/m0/s1 checkY
  • Key:PJMNEPMSGCRSRC-IEVKOWOJSA-N checkY

4-雄烯-3,6,17-三酮(英语:4-Androstene-3,6,17-trione)是一种营养补充品和药物,能提高体内雄激素/雌激素的比例,被世界反运动禁药机构禁止使用,可在尿检中发现[3][4]

参考资料

  1. ^ The World Anti-Doping Code: The 2012 Prohibited List (PDF). World Anti-Doping Agency. [2012-07-17]. (原始内容存档 (PDF)于2012-05-13). 
  2. ^ Huyue Zhang, Guanghui Deng, Zhuibai Qiu. HIGH-YIELD SYNTHESIS OF ANDROST-4-ENE-3,6,17-TRIONE AND ANDROST-4-ENE-3B,6B,17B- TRIOL. Organic Preparations and Procedures International. 2008-08, 40 (4): 395–398 [2021-02-01]. ISSN 0030-4948. doi:10.1080/00304940809458100 (英语). 
  3. ^ Van Thuyne W, Van Eenoo P, Mikulcíková P, Deventer K, Delbeke FT. Detection of androst-4-ene-3,6,17-trione (6-OXO) and its metabolites in urine by gas chromatography-mass spectrometry in relation to doping analysis. Biomed. Chromatogr. 2005, 19 (9): 689–95. PMID 15828056. doi:10.1002/bmc.496. 
  4. ^ Deventer, K; Vaneenoo, P; Mikulcikova, P; Vanthuyne, W; Delbeke, F. Quantitative analysis of androst-4-ene-3,6,17-trione and metabolites in human urine after the administration of a food supplement by liquid chromatography/ion trap-mass spectrometry. Journal of Chromatography B. 2005, 828 (1–2): 21–26. PMID 16213800. doi:10.1016/j.jchromb.2005.08.024. 

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