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伊波加明

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伊波加明
Skeletal formula of ibogamine
Ball-and-stick model of the ibogamine molecule
臨床資料
ATC碼
  • 未分配
識別資訊
  • [6R-(6α,6aβ,7β,9α)]-7-ethyl-6,6a,7,8,9,10,12,13-octahydro-6,9-methano-5H-pyrido[1',2':1,2]azepino[4,5-b]indole
CAS號481-87-8  checkY
PubChem CID
ChemSpider
ChEBI
CompTox Dashboard英語CompTox Chemicals Dashboard (EPA)
化學資訊
化學式C19H24N2
摩爾質量280.42 g·mol−1
3D模型(JSmol英語JSmol
  • CC[C@H]1C[C@@H]2C[C@@H]3[C@H]1N(C2)CCC4=C3NC5=CC=CC=C45
  • InChI=1S/C19H24N2/c1-2-13-9-12-10-16-18-15(7-8-21(11-12)19(13)16)14-5-3-4-6-17(14)20-18/h3-6,12-13,16,19-20H,2,7-11H2,1H3/t12-,13+,16+,19+/m1/s1 checkY
  • Key:LRLCVRYKAFDXKU-YGOSVGOTSA-N checkY

伊波加明(英語:Ibogamine)是一種含氮有機化合物,化學式C19H24N2,是山馬茶Tabernaemontana divaricata)等植物中提取的活性生物鹼,作為抗成癮抗驚厥藥物研發。[1][2][3]

衍生物

參考文獻

  1. ^ Bartlett MF, Dickel DF, Taylor WI. The Alkaloids of Tabernanthe iboga. Part IV.1 The Structures of Ibogamine, Ibogaine, Tabernanthine and Voacangine. Journal of the American Chemical Society. 1958, 80 (1): 126–136. doi:10.1021/ja01534a036. 
  2. ^ Kuehne ME, Reider PJ. A synthesis of ibogamine. The Journal of Organic Chemistry. 1985, 50 (9): 1464–1467. doi:10.1021/jo00209a020. 
  3. ^ Rastogi K, Kapil RS, Popli SP. New alkaloids from Tabernaemontana divaricata.. Phytochemistry. January 1980, 19 (6): 1209–1212. Bibcode:1980PChem..19.1209R. doi:10.1016/0031-9422(80)83085-8. 

外部連結