3-吡啶基煙酰胺

3-吡啶基煙酰胺
	IUPAC名; N-pyridin-3-ylpyridine-3-carboxamide
別名	3-pna; N-(3-吡啶基)煙酰胺
識別
CAS號	13160-06-0
ChemSpider	175548
SMILES	O=C(Nc1cccnc1)c2cccnc2;
性質
化學式	C11H9N3O
摩爾質量	199.20 g/mol g·mol⁻¹
密度	1.287 g/cm3
沸點	286.08 °C（559 K）
結構
偶極矩	0 D
相關物質
相關化學品	N-2-吡啶基-2-吡啶硫代甲酰胺
	若非註明，所有數據均出自標準狀態（25 ℃，100 kPa）下。

3-吡啶基煙酰胺（3-pna）是一種雙足的雙吡啶有機配體，可由煙酰氯和3-氨基吡啶的反應製備。^[1]其吡啶環上的氮原子，如其異構體4-吡啶基煙酰胺上的，可以將其孤對電子配位至金屬陽離子，允許其橋接金屬中心並作為配位聚合物中的雙齒配體。^[2]^[3]^[4]^[5]^[6]它可用於合成具有潛在應用可能的氣體吸附性能的聚合物。^[2]^[3]

參考文獻

^ Zheng, X.; Salgia, S. R.; Thompson, W. B.; Dillingham, E. O.; Bond, S. E.; Feng, Z.; Prasad, K. R.; Gollamudi, R. Design and Synthesis of Piperidine-3-carboxamides as Human Platelet Aggregation Inhibitors. Journal of Medicinal Chemistry. 1995, 38 (1): 180–188. PMID 7837229. doi:10.1021/jm00001a023.
^ ^2.0 ^2.1 Uemura, K.; Kitagawa, S.; Fukui, K. I.; Saito, K. A Contrivance for a Dynamic Porous Framework: Cooperative Guest Adsorption Based on Square Grids Connected by Amide−Amide Hydrogen Bonds. Journal of the American Chemical Society. 2004, 126 (12): 3817–3828. PMID 15038736. doi:10.1021/ja039914m.
^ ^3.0 ^3.1 Uemura, K.; Kitagawa, S.; Kondo, M.; Fukui, K. I.; Kitaura, R.; Chang, H. C.; Mizutani, T. Novel Flexible Frameworks of Porous Cobalt(II) Coordination Polymers That Show Selective Guest Adsorption Based on the Switching of Hydrogen-Bond Pairs of Amide Groups. Chemistry: A European Journal. 2002, 8 (16): 3586. doi:10.1002/1521-3765(20020816)8:16<3586::AID-CHEM3586>3.0.CO;2-K.
^ Kumar, D. K.; Das, A.; Dastidar, P. Supramolecular structural diversities in the metal?organic frameworks derived from pyridylamide ligands: Studying the effects of ligating topologies, hydrogen bonding backbone of the ligands and counter anions. CrystEngComm. 2007, 9 (7): 548. doi:10.1039/B701782K.
^ Banerjee, S.; Adarsh, N. N.; Dastidar, P. Selective Separation of the Sulfate Anion by in Situ Crystallization of CdII Coordination Compounds Derived from Bis(pyridyl) Ligands Equipped with a Urea/Amide Hydrogen-Bonding Backbone. European Journal of Inorganic Chemistry. 2010, 2010 (24): 3770. doi:10.1002/ejic.201000359.
^ Kumar, D. K.; Das, A.; Dastidar, P. Conformation dependent network structures in the coordination polymers derived from pyridylisonicotinamides, carboxylates and Co(ii): Entrapment of (H2O)14 water cluster of an unprecedented topology. CrystEngComm (Royal Society of Chemistry). 2007, 9 (10): 895. doi:10.1039/B705851A.

[1] Zheng, X.; Salgia, S. R.; Thompson, W. B.; Dillingham, E. O.; Bond, S. E.; Feng, Z.; Prasad, K. R.; Gollamudi, R. Design and Synthesis of Piperidine-3-carboxamides as Human Platelet Aggregation Inhibitors. Journal of Medicinal Chemistry. 1995, 38 (1): 180–188. PMID 7837229. doi:10.1021/jm00001a023.

[GTS-2] 2.0 ^2.1 Uemura, K.; Kitagawa, S.; Fukui, K. I.; Saito, K. A Contrivance for a Dynamic Porous Framework: Cooperative Guest Adsorption Based on Square Grids Connected by Amide−Amide Hydrogen Bonds. Journal of the American Chemical Society. 2004, 126 (12): 3817–3828. PMID 15038736. doi:10.1021/ja039914m.

[QQ-3] 3.0 ^3.1 Uemura, K.; Kitagawa, S.; Kondo, M.; Fukui, K. I.; Kitaura, R.; Chang, H. C.; Mizutani, T. Novel Flexible Frameworks of Porous Cobalt(II) Coordination Polymers That Show Selective Guest Adsorption Based on the Switching of Hydrogen-Bond Pairs of Amide Groups. Chemistry: A European Journal. 2002, 8 (16): 3586. doi:10.1002/1521-3765(20020816)8:16<3586::AID-CHEM3586>3.0.CO;2-K.

[4] Kumar, D. K.; Das, A.; Dastidar, P. Supramolecular structural diversities in the metal?organic frameworks derived from pyridylamide ligands: Studying the effects of ligating topologies, hydrogen bonding backbone of the ligands and counter anions. CrystEngComm. 2007, 9 (7): 548. doi:10.1039/B701782K.

[5] Banerjee, S.; Adarsh, N. N.; Dastidar, P. Selective Separation of the Sulfate Anion by in Situ Crystallization of CdII Coordination Compounds Derived from Bis(pyridyl) Ligands Equipped with a Urea/Amide Hydrogen-Bonding Backbone. European Journal of Inorganic Chemistry. 2010, 2010 (24): 3770. doi:10.1002/ejic.201000359.

[6] Kumar, D. K.; Das, A.; Dastidar, P. Conformation dependent network structures in the coordination polymers derived from pyridylisonicotinamides, carboxylates and Co(ii): Entrapment of (H2O)14 water cluster of an unprecedented topology. CrystEngComm (Royal Society of Chemistry). 2007, 9 (10): 895. doi:10.1039/B705851A.

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