M34細胞
M34是一種人類皮膚黑色素瘤細胞系[1]，特點是其β2-微球蛋白基因發生了TTCT四鹼基刪失形成終止密碼子造成了無義突變[2]，常用於生物醫學研究[3]。
參考資料
- ^ Jiang, X; Zhou, J; Yuen, NK; Corless, CL; Heinrich, MC; Fletcher, JA; Demetri, GD; Widlund, HR; Fisher, DE; Hodi, FS. Imatinib targeting of KIT-mutant oncoprotein in melanoma.. Clinical cancer research : an official journal of the American Association for Cancer Research. 2008-12-01, 14 (23): 7726–32. PMID 19047099. doi:10.1158/1078-0432.CCR-08-1144.
- ^ Fernández, MA; Ruiz-Cabello, F; Oliva, MR; Cabrera, T; Jimenez, P; López Nevot, MA; Garrido, F. Beta2-microglobulin gene mutation is not a common mechanism of HLA class I total loss in human tumors.. International journal of clinical & laboratory research. 2000, 30 (2): 87–92. PMID 11043502. doi:10.1007/BF02874164.
- ^ Kucukkaraduman, B; Turk, C; Fallacara, AL; Isbilen, M; Senses, KM; Ayyildiz, ZO; Akbar, MW; Lotem, M; Botta, M; Gure, AO. Predictive Gene Signature for Pyrazolopyrimidine Derivative c-Src Inhibitor 10a Sensitivity in Melanoma Cells.. ACS medicinal chemistry letters. 2020-05-14, 11 (5): 928–932. PMID 32435407. doi:10.1021/acsmedchemlett.9b00679.
外部連結
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