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黃夾次苷

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黃夾次苷
臨床資料
其他名稱(3S,5R,10R,13R,14S,17R)- 3-[(2S,5R)- 3,5-dihydroxy- 4-methoxy- 6-methyloxan- 2-yl]oxy- 14-hydroxy- 13-methyl- 17-(5-oxo-2H-furan-3-yl)- 1,2,3,4,5,6,7,8,9,11,12,15,16,17- tetradecahydrocyclopenta[a]phenanthrene- 10-carbaldehyde
ATC碼
識別資訊
  • (3β,5β,8ξ,9ξ)- 3-[(6-deoxy- 3-O-methyl- α-D- glycero- hexopyranosyl)oxy]- 14-hydroxy- 19-oxocard- 20(22)enolide
CAS號1182-87-2  checkY
PubChem CID
ChemSpider
ChEMBL
CompTox Dashboard英語CompTox Chemicals Dashboard (EPA)
ECHA InfoCard100.013.327 編輯維基數據鏈接
化學資訊
化學式C30H44O9
摩爾質量548.665 g/mol
3D模型(JSmol英語JSmol
  • O=C\1OC/C(=C/1)[C@H]6CC[C@@]5(O)[C@]6(C)CC[C@H]3[C@H]5CC[C@@H]4C[C@@H](O[C@@H]2O[C@@H](C)[C@H](O)[C@@H](OC)[C@@H]2O)CC[C@]34C=O
  • InChI=1S/C30H44O9/c1-16-24(33)26(36-3)25(34)27(38-16)39-19-6-10-29(15-31)18(13-19)4-5-22-21(29)7-9-28(2)20(8-11-30(22,28)35)17-12-23(32)37-14-17/h12,15-16,18-22,24-27,33-35H,4-11,13-14H2,1-3H3/t16-,18+,19-,20+,21-,22+,24-,25-,26+,27-,28+,29+,30-/m0/s1 checkY
  • Key:PMTSPAGBAFCORP-HBUONDEYSA-N checkY

黃夾次苷(英語:Peruvoside或稱為黃花夾竹桃苷,英語:cannogenin thevetoside)是一種強心苷[1],用於治療心臟衰竭[2],來源於黃花夾竹桃(學名:Cascabela thevetia,曾用學名:Thevetia neriifolia[2]

參考文獻

  1. ^ Arora, R. B.; Rangaswami, S. Peruvoside and Other Cardiotonic Glycoside[s] of Thevetia neriifolia Juss: Chemical, Pharmacological, and Clinical Studies. New Delhi, India: Thomson. 1972. LCCN 78900408. 
  2. ^ 2.0 2.1 Bhatia, M. L.; Manchanda, S. C.; Roy, S. B. Haemodynamic Studies with Peruvoside in Human Congestive Heart Failure. British Medical Journal. 1970, 3 (5725): 740–743. PMC 1701679可免費查閱. PMID 4919553. doi:10.1136/bmj.3.5725.740.