2-溴咪唑
2-溴咪唑 | |
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別名 | 2-溴-1H-咪唑 |
識別 | |
CAS號 | 16681-56-4 ![]() |
PubChem | 2773261 |
SMILES |
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性質 | |
化學式 | C3H3BrN2 |
摩爾質量 | 146.97 g·mol−1 |
熔點 | 197—198 °C(470—471 K)[1] |
若非註明,所有數據均出自標準狀態(25 ℃,100 kPa)下。 |
2-溴咪唑是一種有機溴化合物,化學式為C3H3BrN2。它可由咪唑和二乙酸碘苯、溴化鈉在乙腈水溶液中反應[2],或和1-丁基-3-甲基吡啶鎓三溴化物在水中反應[3]製得。它和2-(2-溴苯基)-4,5-二苯基咪唑、碳酸鉀在碘化亞銅、鄰菲囉啉催化下反應,可以得到2,3-二苯基二咪唑並[1,2-a:1',2'-c]喹唑啉。[4]
參考文獻
- ^ Kenneth L. Kirk The Journal of Organic Chemistry 1978 43 (22), 4381-4383 doi:10.1021/jo00416a033
- ^ PhI(OAc)2/NaX-mediated halogenation providing access to valuable synthons 3-haloindole derivatives. New Journal of Chemistry. 2018. 23. doi:10.1039/C8NJ03822H.
- ^ An efficient, rapid, and regioselective bromination of anilines and phenols with 1-butyl-3-methylpyridinium tribromide as a new reagent/solvent under mild conditions. Tetrahedron Letters. 2009. 50 (9). doi:10.1016/j.tetlet.2008.12.053.
- ^ An efficient synthesis of diimidazo[1,2-a:1′,2′-c]quinazolines via a copper-catalyzed double Ullmann cross-coupling reaction. Tetrahedron. 2021. 81. 131918. doi:10.1016/j.tet.2020.131918.