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鳞状细胞癌抗原-2

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鳞状细胞癌抗原-2
识别号
别名SERPINB4;, LEUPIN, PI11, SCCA-2, SCCA1, SCCA2, serpin family B member 4
外部IDOMIM600518 MGI2683293 HomoloGene76659 GeneCardsSERPINB4
基因位置(人类
18号染色体
染色体18号染色体[1]
18号染色体
鳞状细胞癌抗原-2的基因位置
鳞状细胞癌抗原-2的基因位置
基因座18q21.33起始63,637,259 bp[1]
终止63,644,256 bp[1]
直系同源
物种人类小鼠
Entrez
Ensembl
UniProt
mRNA​序列

​NM_002974
​NM_175041

NM_198680

蛋白序列

NP_002965
​NP_778206

NP_941373

基因位置​(UCSC)Chr 18: 63.64 – 63.64 MbChr 1: 107.08 – 107.21 Mb
PubMed​查找[3][4]
维基数据
查看/编辑人类查看/编辑小鼠

鳞状细胞癌抗原-2(英语:Squamous cell carcinoma antigen-2,缩写SCCA-2SCCA2,也称为丝氨酸蛋白酶抑制剂家族B亚家族成员4serpin family B member 4,缩写SERPINB4)是一个人类18号染色体上的基因,编码一种丝氨酸蛋白酶抑制剂蛋白,是鳞状细胞癌肿瘤标志物[5][6][7]

参考文献

  1. ^ 1.0 1.1 1.2 GRCh38: Ensembl release 89: ENSG00000206073 - Ensembl, May 2017
  2. ^ 2.0 2.1 2.2 GRCm38: Ensembl release 89: ENSMUSG00000073602 - Ensembl, May 2017
  3. ^ Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine. 
  4. ^ Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine. 
  5. ^ Schneider SS, Schick C, Fish KE, Miller E, Pena JC, Treter SD, Hui SM, Silverman GA. A serine proteinase inhibitor locus at 18q21.3 contains a tandem duplication of the human squamous cell carcinoma antigen gene. Proc Natl Acad Sci U S A. May 1995, 92 (8): 3147–51. Bibcode:1995PNAS...92.3147S. PMC 42122可免费查阅. PMID 7724531. doi:10.1073/pnas.92.8.3147可免费查阅. 
  6. ^ Sakata Y, Arima K, Takai T, Sakurai W, Masumoto K, Yuyama N, Suminami Y, Kishi F, Yamashita T, Kato T, Ogawa H, Fujimoto K, Matsuo Y, Sugita Y, Izuhara K. The squamous cell carcinoma antigen 2 inhibits the cysteine proteinase activity of a major mite allergen, Der p 1. J Biol Chem. Feb 2004, 279 (7): 5081–7. PMID 14630915. doi:10.1074/jbc.M311585200可免费查阅. 
  7. ^ Entrez Gene: SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4. [2023-04-10]. (原始内容存档于2010-12-05). 

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