BSPP

BSPP
临床资料
ATC码	未分配;
识别信息
	IUPAC命名法 2,6-di-tert-butyl-4-{[1-(hydroxymethyl)cyclopentyl]methyl}phenol; ;
CAS号	938174-18-6
PubChem CID	16079861;
ChemSpider	17238838 ;
CompTox Dashboard（英语：CompTox Chemicals Dashboard） (EPA)	DTXSID001028427 ;
化学信息
化学式	C21H34O2
摩尔质量	318.50 g·mol−1
3D模型（JSmol（英语：JSmol））	交互式图像;
	SMILES C(C)(C)(C)C1=C(C(=CC(=C1)CC1(CCCC1)CO)C(C)(C)C)O;
	InChI InChI=1S/C21H34O2/c1-19(2,3)16-11-15(12-17(18(16)23)20(4,5)6)13-21(14-22)9-7-8-10-21/h11-12,22-23H,7-10,13-14H2,1-6H3 ; Key:CTFKOMUXSHQLLL-UHFFFAOYSA-N ;

BSPP（化学名： 2,6-二叔丁基-4-(3-羟基-2-螺戊基丙基)-苯酚，2,6-di-tert-butyl-4-(3-hydroxy-2-spiropentylpropyl)-phenol）是一种有机化合物，是GABA_B 受体的正向别构调节剂，其作用效果和CGP7930与BHFF类似。^[1]^[2]

参考文献

^ Kerr DI, Khalafy J, Ong J, Perkins MV, Prager RH, Puspawati NM, Rimaz M. Synthesis and biological activity of allosteric modulators of GABAB receptors, part 2. 3-(2, 6-bis-tert-butyl-4-hydroxyphenyl) propanols.. Australian Journal of Chemistry. September 2006, 59 (7): 457–62. doi:10.1071/CH06164.
^ Parker DA, Marino V, Ong J, Puspawati NM, Prager RH. The CGP7930 analogue 2,6-di-tert-butyl-4-(3-hydroxy-2-spiropentylpropyl)-phenol (BSPP) potentiates baclofen action at GABA(B) autoreceptors. Clinical and Experimental Pharmacology & Physiology. September 2008, 35 (9): 1113–5. PMID 18430050. doi:10.1111/j.1440-1681.2008.04948.x.

外部链接

维基共享资源上的相关多媒体资源：BSPP

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[1] Kerr DI, Khalafy J, Ong J, Perkins MV, Prager RH, Puspawati NM, Rimaz M. Synthesis and biological activity of allosteric modulators of GABAB receptors, part 2. 3-(2, 6-bis-tert-butyl-4-hydroxyphenyl) propanols.. Australian Journal of Chemistry. September 2006, 59 (7): 457–62. doi:10.1071/CH06164.

[pmid18430050-2] Parker DA, Marino V, Ong J, Puspawati NM, Prager RH. The CGP7930 analogue 2,6-di-tert-butyl-4-(3-hydroxy-2-spiropentylpropyl)-phenol (BSPP) potentiates baclofen action at GABA(B) autoreceptors. Clinical and Experimental Pharmacology & Physiology. September 2008, 35 (9): 1113–5. PMID 18430050. doi:10.1111/j.1440-1681.2008.04948.x.

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