Comins试剂
Comins试剂 | |
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识别 | |
CAS号 | 145100-51-2 ![]() |
PubChem | 388544 |
ChemSpider | 344376 |
SMILES |
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InChI |
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InChIKey | TUFGVZMNGTYAQD-UHFFFAOYAK |
性质 | |
化学式 | C7H3ClF6N2O4S2 |
摩尔质量 | 392.68 g·mol−1 |
外观 | 白色固体 |
熔点 | 45 °C(318 K) |
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。 |
Comins试剂是一种三氟甲磺酰化合物,可用于从相应的酮烯醇式合成三氟甲磺酸酯。 [1]
![Sample Reaction With Comin's Reagent](http://images.weserv.nl/?url=//upload.wikimedia.org/wikipedia/commons/thumb/2/22/SampleReactionWithCominsReagent.png/500px-SampleReactionWithCominsReagent.png)
它最早由Daniel Comins于1992年报道。[2] 三氟甲磺酸乙烯酯对于铃木反应来说是很有用的底物。[3]
参考文献
- ^ Mundy, Bradford P.; Ellerd, Michael G.; Favaloro, Frank G., Jr. Name Reactions and Reagents in Organic Synthesis 2nd. 2005. ISBN 0471228540.
- ^ Comins, Daniel L.; Dehghani, Ali. Pyridine-Derived Triflating Reagents: An Improved Preparation of Vinyl Triflates from Metallo Enolates. Tetrahedron Letters. 1992, 33 (42): 6299–6302. doi:10.1016/S0040-4039(00)60957-7.
- ^ Miyaura, Norio; Suzuki, Akira. Palladium-Catalyzed Cross-Coupling Reactions of Organoboron Compounds. Chemical Reviews. 1995, 95: 2457–2483. doi:10.1021/cr00039a007.