十一烯酸睾酮
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| 臨床資料 | |
|---|---|
| 商品名 | Durasteron、Triolandren |
| 其他名稱 | TUe、睾酮十一烯酸酯 |
| 给药途径 | 静脉注射 |
| 藥物類別 | 雄激素、合成代谢类固醇、雄激素酯 |
| 识别信息 | |
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| CAS号 | 29430-26-0  |
| PubChem CID | |
| ChemSpider | |
| UNII | |
| CompTox Dashboard (EPA) | |
| ECHA InfoCard | 100.045.099 |
| 化学信息 | |
| 化学式 | C30H46O3 |
| 摩尔质量 | 454.70 g·mol−1 |
| 3D模型（JSmol） | |
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十一烯酸睾酮，缩写TUe，是一种雄激素/合成代谢类固醇药物和雄激素酯，已不再上市。[1][2][3]它是Durasteron和Triolandren的成分，这两种药物是长效的睾酮酯油溶液混合物，通过肌肉注射给药。[4][5][6][7]
参见
参考资料
- ^ Shapiro S, Weinburg K, Freedman L. Notes - Long-Acting Androgens. The Journal of Organic Chemistry. 1956, 21 (11): 1300–1302. ISSN 0022-3263. doi:10.1021/jo01117a602.
- ^ Gould D, Finckenor L, Hershberg EB, Cassidy J, Perlman PL. Long-acting Testosterone Esters. Some Considerations on their Biological Utilization1. Journal of the American Chemical Society. 1957, 79 (16): 4472–4475. ISSN 0002-7863. doi:10.1021/ja01573a061.
- ^ US 2855341,Meier, R; A Wettstein & E Lang,「Testosterone compositions」,发表于1958-10-07,指定于Ciba pharmaceutical Products, Inc.
- ^ Schuermann H, Doepfmer R. Fertilitätsstörungen beim Manne. Springer-Verlag. 1960: 260–. ISBN 978-3-642-94784-1.
- ^ Ufer J. Hormontherapie in der Frauenheilkunde: Grundlagen und Praxis. Gruyter. 1960: 153. ISBN 9783111138770.
- ^ Aakvaag A, Vogt JH. Plasma testosterone values in different forms of testosterone treatment. Acta Endocrinologica. March 1969, 60 (3): 537–542. PMID 5395873. doi:10.1530/acta.0.0600537.
Triolandren®, for intramuscular use, kindly supplied by Ciba, Basel, through Kobro 8c Co., Oslo, containing three different testosterone esters, in the following amounts of testosterone equivalents per ml oil: propionate 20 mg; valerate 80 mg; undecylenate 150 mg.
- ^ Zachmann M, Prader A. Anabolic and androgenic effect of testosterone in sexually immature boys and its dependency on growth hormone. The Journal of Clinical Endocrinology and Metabolism. January 1970, 30 (1): 85–95. PMID 4311616. doi:10.1210/jcem-30-1-85.
Triolandren, CIBA; 250 mg of this preparation contains 20 mg of testosterone propionate, 80 mg of testosterone-n-valerianate, and 150 mg of testosterone undecylenate—250 mg thus contains 173.8 mg of testosterone; the remaining 76.2 mg consists of the ester components [...]
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