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鼻孢子蟲病

维基百科,自由的百科全书
鼻孢子蟲病
口腔被鼻孢子蟲感染的病患
病因西氏鼻孢子蟲英语Rhinosporidium seeberi感染
治療切除病灶
分类和外部资源
醫學專科傳染病學
ICD-111F56
ICD-9-CM117.0
DiseasesDB31328
eMedicine227734
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鼻孢子蟲病(Rhinosporidiosis)又稱鼻芽孢蟲病,是西氏鼻孢子蟲英语Rhinosporidium seeberi感染人類、其他哺乳動物與鳥類所造成的疾病[註 1]。此病最早於1896年由阿根廷醫師吉列爾摩·西伯(Guillermo Rodolfo Seeber)在一名病患中發現[3],其病原過去長期被認為屬於真菌,近代分子證據才發現其屬於中菌動物動物總界基群的類群)[4]

鼻孢子蟲病最常見於南亞南美洲非洲等熱帶地區,其中印度斯里蘭卡的感染率最高[4][5][6][7],且男性感染率高於女性[5]。感染途徑可能是於池塘與湖泊中經動物的糞便感染[4]

西氏鼻孢子蟲大多感染粘膜,造成如草莓狀的息肉[4],其中約七成患者為鼻咽被感染,約15%則為眼睛結膜被感染,其他身體部位的感染也曾被報導。此病常為長期且無痛的感染,極少有造成全身感染而致死的案例[5];其治療方法一般為切除病灶,有時事後再施以達普頌抗生素以預防患部發生細菌感染[1]

註腳

  1. ^ 另一種鼻孢子蟲有感染兩生類的紀錄[1][2]

參考文獻

  1. ^ 1.0 1.1 Mayet, Huzaifah; Reddy, Denasha L.; Alvarez, Tika Bello; Atiya, Yahya; Govender, Nelesh P.; Birkhead, Monica; Maphanga, Tsidiso; Pather, Sugeshnee. Case Report of Nasal Rhinosporidiosis in South Africa. Emerging Infectious Diseases. 2024-04, 30 (4). doi:10.3201/eid3004.240018. 
  2. ^ Scheid, P; Balczun, C; Dehling, Jm; Ammon, A; Sinsch, U. Rhinosporidiosis in African reed frogs Hyperolius spp. caused by a new species of Rhinosporidium. Diseases of Aquatic Organisms. 2015-07-23, 115 (2): 111–120. doi:10.3354/dao02888. 
  3. ^ Mendoza, Leonel; Vilela, Raquel. Anomalous fungal and fungal-like infections: lacaziosis, pythiosis, and rhinosporidiosis. Clinical Mycology. 2009: 403–415. doi:10.1016/B978-1-4160-5680-5.00018-9. 
  4. ^ 4.0 4.1 4.2 4.3 Prakash, M; Johnny, JCarlton. Rhinosporidiosis and the pond. Journal of Pharmacy And Bioallied Sciences. 2015, 7 (5): 59. doi:10.4103/0975-7406.155804. 
  5. ^ 5.0 5.1 5.2 Duane R Hospenthal. Rhinosporidiosis. Medscape. 2023-02-15. 
  6. ^ Berrocal, Alexis; López, Alfonso. Nasal rhinosporidiosis in a mule. The Canadian Veterinary Journal. March 2007, 48 (3): 305–306. PMC 1800950可免费查阅. PMID 17436910. 
  7. ^ Morelli, Luca; Polce, Mario; Piscioli, Francesco; Del Nonno, Franca; Covello, Renato; Brenna, Alessia; Cione, Antonio; Licci, Stefano. Human nasal rhinosporidiosis: an Italian case report. Diagnostic Pathology. December 2006, 1 (1): 25. PMC 1560165可免费查阅. PMID 16945122. doi:10.1186/1746-1596-1-25可免费查阅.