2-氯丁酸
2-氯丁酸 | |
---|---|
![]() | |
英文名 | 2-chlorobutanoic acid α-chlorobutyric acid |
别名 | α-氯丁酸 |
识别 | |
CAS号 | 4170-24-5 ![]() |
SMILES |
|
性质 | |
化学式 | C4H7ClO2 |
摩尔质量 | 122.55 g·mol⁻¹ |
密度 | 1.189 g/cm3(25 °C)[1] |
熔点 | 76.2—77 °C(349.3—350.1 K)[2] |
危险性 | |
主要危害 | 腐蚀性 |
相关物质 | |
其他阴离子 | 2-氟丁酸、2-溴丁酸、 2-碘丁酸 |
相关化学品 | 氯乙酸、2-氯丙酸、 3-氯丁酸、4-氯丁酸 |
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。 |
2-氯丁酸是一种有机化合物,化学式为C4H7O2Cl。它可由正丁酸和氯气[3][4]或氯磺酸[5]在一定条件下反应得到。2-氯丁酸经过胺化反应可以得到2-氨基丁酰胺;[6]它也能和草酰氯反应,得到2-氯丁酰氯。[7]
参考文献
- ^ Horn, R. H.; Miller, R. B.; Slater, S. N. Preparation of some 1-chloroalkane-1-carboxylic acids. Journal of the Chemical Society, 1950. 2900-2901
- ^ Bernard I. Halperin, Hugh B. Donahoe, Jacob Kleinberg, Calvin A. Vanderwerf. ADDITION OF IODINE (I) 3,5-DINITROBENZOATE TO SIMPLE OLEFINS. The Journal of Organic Chemistry. 1952-04, 17 (4): 623–629 [2019-05-22]. ISSN 0022-3263. doi:10.1021/jo01138a017. (原始内容存档于2019-08-21) (英语).
- ^ Tang, Jihai; Hu, Jingyi; Qiu, Baozeng; Yang, Yun; Qiao, Xu; Chen, Xian; Fei, Zhaoyang; Cui, Mifen. Method for preparing α-chlorinated fatty acids. (2014) CN 103724178 A
- ^ Xia, Jiansheng; Li, Jianjun; Zhou, Zhangxing; Qian, Gang; Chen, Dexiang. Process for preparation of 2-aminobutyric acid. (2014) CN 103787903 A
- ^ Prabhakaran, Prabu C.; Sharma, Anil; Gorman, Christopher. Chlorosulfonic acid. e-EROS Encyclopedia of Reagents for Organic Synthesis (2008), 1-6.
- ^ Liu, Liping; Qian, Gang; Wang, Fei; Zhao, Guangrong; Tang, Jingyu. Process for preparation of 2-aminobutyramide. (2015) CN 105198768 A
- ^ Masayoshi Jin, Laksmikanta Adak, Masaharu Nakamura. Iron-Catalyzed Enantioselective Cross-Coupling Reactions of α-Chloroesters with Aryl Grignard Reagents. Journal of the American Chemical Society. 2015-06-10, 137 (22): 7128–7134 [2019-05-22]. ISSN 0002-7863. doi:10.1021/jacs.5b02277. (原始内容存档于2019-08-21) (英语).