IgG4相關性疾病

IgG4相關性疾病; IgG4-related disease
	低倍視野下的相關性前列腺炎：前列腺間質發生密集的炎性浸潤和纖維化（HE染色，100倍放大）
分類和外部資源
醫學專科	免疫學/風濕病學
ICD-11	4A43.0
Orphanet	284264
	[編輯此條目的維基數據]

IgG4相關性疾病（英語：IgG4-related disease），縮寫 IgG4-RD，以前稱為IgG4相關全身性疾病（英語：IgG4-related systemic disease）是一類可在多種器官中發生的慢性、進行性的炎症疾病，並伴隨著組織淋巴細胞浸潤和漿細胞大量分泌IgG4以及不同程度的纖維化^[1]。約有 51–70% 的病人在急性期血清IgG4顯著升高，因而得名^[2]。主要發病人群是中老年男性，口服糖皮質激素是此病的一線療法^[3]。

參考文獻

^ Wallace, Zachary S.; Deshpande, Vikram; Mattoo, Hamid; Mahajan, Vinay S.; Kulikova, Maria; Pillai, Shiv; Stone, John H. IgG4-Related Disease: Clinical and Laboratory Features in One Hundred Twenty-Five Patients. Arthritis & Rheumatology. 26 August 2015, 67 (9): 2466–2475. PMC 4621270 . PMID 25988916. doi:10.1002/art.39205.
^ Vikram Deshpande; Yoh Zen; John KC Chan; Eunhee E Yi; Yasuharu Sato; Tadashi Yoshino; Günter Klöppe; J Godfrey Heathcote; Arezou Khosroshahi; Judith A Ferry; Rob C Aalberse; Donald B Bloch; William R Brugge; Adrian C Bateman; Mollie N Carruthers; Suresh T Chari; Wah Cheuk; Lynn D Cornell; Carlos Fernandez-Del Castillo; David G Forcione; Daniel L Hamilos; Terumi Kamisawa; Satomi Kasashima; Shigeyuki Kawa; Mitsuhiro Kawano; Gregory Y Lauwers; Yasufumi Masaki; Yasuni Nakanuma; Kenji Notohara; Kazuichi Okazaki; Ji Kon Ryu; Takako Saeki; Dushyant V Sahani; Thomas C Smyrk; James R Stone; Masayuki Takahira; George J Webster; Motohisa Yamamoto; Giuseppe Zamboni; Hisanori Umehara; John H Stone. Consensus statement on the pathology of IgG4-related disease. Modern Pathology. 18 May 2012, 25 (9): 1181–1192. PMID 22596100. doi:10.1038/modpathol.2012.72.
^ John H. Stone; Arezou Khosroshahi; Vikram Deshpande; John K. C. Chan; J. Godfrey Heathcote; Rob Aalberse; Atsushi Azumi; Donald B. Bloch; William R. Brugge; Mollie N. Carruthers; Wah Cheuk; Lynn Cornell; Carlos Fernandez-Del Castillo; Judith A. Ferry; David Forcione; Günter Klöppe; Daniel L. Hamilos; Terumi Kamisawa; Satomi Kasashima; Shigeyuki Kawa; Mitsuhiro Kawano; Yasufumi Masaki; Kenji Notohara; Kazuichi Okazaki; Ji Kon Ryu; Takako Saeki; Dushyant Sahani; Yasuharu Sato; Thomas Smyrk; James R. Stone; Masayuki Takahira; Hisanori Umehara; George Webster; Motohisa Yamamoto; Eunhee Yi; Tadashi Yoshino; Giuseppe Zamboni; Yoh Zen; Suresh Chari. Recommendations for the nomenclature of IgG4-related disease and its individual organ system manifestations. Arthritis & Rheumatism. October 2012, 64 (10): 3061–3067. PMC 5963880 . PMID 22736240. doi:10.1002/art.34593.

外部連結

Overview of IgG4-related disease（頁面存檔備份，存於網際網路檔案館） - UpToDate's article on IgG4-related disease.
DermNet NZ（頁面存檔備份，存於網際網路檔案館） entry

[pmid25988916-1] Wallace, Zachary S.; Deshpande, Vikram; Mattoo, Hamid; Mahajan, Vinay S.; Kulikova, Maria; Pillai, Shiv; Stone, John H. IgG4-Related Disease: Clinical and Laboratory Features in One Hundred Twenty-Five Patients. Arthritis & Rheumatology. 26 August 2015, 67 (9): 2466–2475. PMC 4621270 . PMID 25988916. doi:10.1002/art.39205.

[pmid22596100-2] Vikram Deshpande; Yoh Zen; John KC Chan; Eunhee E Yi; Yasuharu Sato; Tadashi Yoshino; Günter Klöppe; J Godfrey Heathcote; Arezou Khosroshahi; Judith A Ferry; Rob C Aalberse; Donald B Bloch; William R Brugge; Adrian C Bateman; Mollie N Carruthers; Suresh T Chari; Wah Cheuk; Lynn D Cornell; Carlos Fernandez-Del Castillo; David G Forcione; Daniel L Hamilos; Terumi Kamisawa; Satomi Kasashima; Shigeyuki Kawa; Mitsuhiro Kawano; Gregory Y Lauwers; Yasufumi Masaki; Yasuni Nakanuma; Kenji Notohara; Kazuichi Okazaki; Ji Kon Ryu; Takako Saeki; Dushyant V Sahani; Thomas C Smyrk; James R Stone; Masayuki Takahira; George J Webster; Motohisa Yamamoto; Giuseppe Zamboni; Hisanori Umehara; John H Stone. Consensus statement on the pathology of IgG4-related disease. Modern Pathology. 18 May 2012, 25 (9): 1181–1192. PMID 22596100. doi:10.1038/modpathol.2012.72.

[pmid22736240-3] John H. Stone; Arezou Khosroshahi; Vikram Deshpande; John K. C. Chan; J. Godfrey Heathcote; Rob Aalberse; Atsushi Azumi; Donald B. Bloch; William R. Brugge; Mollie N. Carruthers; Wah Cheuk; Lynn Cornell; Carlos Fernandez-Del Castillo; Judith A. Ferry; David Forcione; Günter Klöppe; Daniel L. Hamilos; Terumi Kamisawa; Satomi Kasashima; Shigeyuki Kawa; Mitsuhiro Kawano; Yasufumi Masaki; Kenji Notohara; Kazuichi Okazaki; Ji Kon Ryu; Takako Saeki; Dushyant Sahani; Yasuharu Sato; Thomas Smyrk; James R. Stone; Masayuki Takahira; Hisanori Umehara; George Webster; Motohisa Yamamoto; Eunhee Yi; Tadashi Yoshino; Giuseppe Zamboni; Yoh Zen; Suresh Chari. Recommendations for the nomenclature of IgG4-related disease and its individual organ system manifestations. Arthritis & Rheumatism. October 2012, 64 (10): 3061–3067. PMC 5963880 . PMID 22736240. doi:10.1002/art.34593.

[1]

[2]

[3]