跳转到内容

氯马唑仑

维基百科,自由的百科全书
氯马唑仑
临床资料
商品名英语Drug nomenclatureClimasol
AHFS/Drugs.com国际药品名称
ATCvet码
法律规范状态
法律规范
识别信息
  • 8-Chloro-6-(2-chlorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine
CAS号59467-77-5
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard英语CompTox Chemicals Dashboard (EPA)
化学信息
化学式C18H13Cl2N3
摩尔质量342.22 g·mol−1
3D模型(JSmol英语JSmol
  • ClC1=CC=CC=C1C2=NCC3=CN=C(C)N3C4=C2C=C(C=C4)Cl

氯马唑仑英语:Climazolam[1];开发代号:Ro21-3982)由瑞士制药公司Gräub以商品名Climasol作为合法兽药引入。[2]氯马唑仑是一种苯二氮䓬类药物,具体来说是罗氏开发的咪唑并苯二氮䓬类衍生物。它与咪达唑仑地西泮的结构相似,在兽医学中用于麻醉动物。[3][4]

参考资料

  1. ^ US 4280957,Walser A, Fryer RI,“Imidazodiazepines and processes therefor”,发行于28 July 1981,指定于Hoffman La Roche 
  2. ^ Climazolam. Drugs.com. [2023-04-05]. (原始内容存档于2017-08-01). 
  3. ^ Ganter M, Kanngiesser M. Effect of ketamine and its combinations with xylazine and climazolam on the circulation and respiration in swine. Zentralbl Veterinarmed A. Aug 1991, 38 (7): 501–509. PMID 1950241. doi:10.1111/j.1439-0442.1991.tb01041.x (德语). 
  4. ^ Bettschart-Wolfensberger R, Taylor PM, Sear JW, Bloomfield MR, Rentsch K, Dawling S. Physiologic effects of anesthesia induced and maintained by intravenous administration of a climazolam-ketamine combination in ponies premedicated with acepromazine and xylazine. American Journal of Veterinary Research. Oct 1996, 57 (10): 1472–1477. PMID 8896687.