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氯馬唑侖

維基百科,自由的百科全書
氯馬唑侖
臨床資料
商品名英語Drug nomenclatureClimasol
AHFS/Drugs.com國際藥品名稱
ATCvet碼
法律規範狀態
法律規範
識別資訊
  • 8-Chloro-6-(2-chlorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine
CAS號59467-77-5
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard英語CompTox Chemicals Dashboard (EPA)
化學資訊
化學式C18H13Cl2N3
摩爾質量342.22 g·mol−1
3D模型(JSmol英語JSmol
  • ClC1=CC=CC=C1C2=NCC3=CN=C(C)N3C4=C2C=C(C=C4)Cl

氯馬唑侖英語:Climazolam[1];開發代號:Ro21-3982)由瑞士製藥公司Gräub以商品名Climasol作為合法獸藥引入。[2]氯馬唑侖是一種苯二氮䓬類藥物,具體來說是羅氏開發的咪唑並苯二氮䓬類衍生物。它與咪達唑侖地西泮的結構相似,在獸醫學中用於麻醉動物。[3][4]

參考資料

  1. ^ US 4280957,Walser A, Fryer RI,「Imidazodiazepines and processes therefor」,發行於28 July 1981,指定於Hoffman La Roche 
  2. ^ Climazolam. Drugs.com. [2023-04-05]. (原始內容存檔於2017-08-01). 
  3. ^ Ganter M, Kanngiesser M. Effect of ketamine and its combinations with xylazine and climazolam on the circulation and respiration in swine. Zentralbl Veterinarmed A. Aug 1991, 38 (7): 501–509. PMID 1950241. doi:10.1111/j.1439-0442.1991.tb01041.x (德語). 
  4. ^ Bettschart-Wolfensberger R, Taylor PM, Sear JW, Bloomfield MR, Rentsch K, Dawling S. Physiologic effects of anesthesia induced and maintained by intravenous administration of a climazolam-ketamine combination in ponies premedicated with acepromazine and xylazine. American Journal of Veterinary Research. Oct 1996, 57 (10): 1472–1477. PMID 8896687.