苯並呋喃,也稱為香豆酮、氧茚、β-苯並呋喃,是雜環芳香有機化合物
合成
苯並呋喃可由煤焦油萃取,也可將2-乙基苯酚脫氫而成。[1]
實驗室方法
實驗室可用多種方法合成苯並呋喃,著名例子有:
用氯乙酸氧-烷化水楊醛,之後脫水得到。[2](環化)並脫羧。[3]
氫氧化物進攻香豆素,重排成苯並呋喃:[4][5][6]
參見
參考資料
- ^ Collin, G.; Höke, H. Ullmann's Encyclopedia of Industrial Chemistry. Weinheim: Wiley-VCH. 2007. ISBN 978-3527306732. doi:10.1002/14356007.l03_l01.
- ^ Albert W. Burgstahler and Leonard R. Worden 「Coumarone」 Organic Syntheses, Collected Volume 5, p.251 (1973). http://www.orgsyn.org/demo.aspx?prep=CV5P0251 (頁面存檔備份,存於網際網路檔案館)
- ^ Burgstahler, A. W. (1966). "Coumarone". Org. Synth. 46: 28; Coll. Vol. 5: 251.
- ^ Perkin, W. H. XXIX. On some New Bromine Derivatives of Coumarin. Journal of the Chemical Society. 1870, 23: 368–371 [2023-05-25]. doi:10.1039/JS8702300368. (原始內容存檔於2022-10-16).
- ^ Perkin, W. H. IV. On some New Derivatives of Coumarin. Journal of the Chemical Society. 1871, 24: 37–55 [2023-05-25]. doi:10.1039/JS8712400037. (原始內容存檔於2022-10-14).
- ^ Bowden, K.; Battah, S. Reactions of Carbonyl Compounds in Basic Solutions. Part 32. The Perkin Rearrangement. Journal of the Chemical Society, Perkin Transactions 2. 1998, 1998 (7): 1603–1606. doi:10.1039/a801538d.